Qt-events.com
Title
QT Prolongation & Beyond
Description
Excerpted from the website:
- The recent agreements and implementation of the international clinical (ICH E14) guidelines will have significant impact on the pharmaceutical industry, forcing companies to reassess the development strategy of their drugs and their impact on cardiac repolarisation and the QT interval. This is likely to result in widespread application of thorough QT studies to assess the safety of drugs and questions the value and predictability of preclinical trials. In addition, more and more studies point to a genetic pre-disposition to QT prolongation, leading specialists to examine the possibility of preventing QT prolongation in sensitive patients. Finally, the recent changes have raised a cost issue throughout the industry leading to the issue of cost effective QT studies.
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