HeartFlo.com When you think Coenzyme Q10, think Heartflo!

Optimize Cellular-Energy Production & Cardiovascular Health with Heartflo and Heartflo plus CoQ10.


HEARTFLO™ AND Heartflo Plus™


• Heartflo™: Formulated with 100% natural Coenzyme Q10 (CoQ10). CoQ10 (ubiquinone) is a naturally occurring enzyme cofactor found in the mitochondria of the body cells. CoQ10 is synthesized endogenously and intracellularly throughout body tissues, particularly the heart, liver, kidney and pancreas. Heartflo™ supports the generation of cellular energy, antioxidant function, and cardiovascular health.*

• Heartflo Plus™: Helps support generation of cellular energy, antioxidant function, cardiovascular and cognitive health with Coenzyme Q10 (CoQ10) and Vitamin E (VE). Heartflo PLUS™ promotes anti-aging and replenishes CoQ10 needs. Heartflo PLUS™ is formulated from natural CoQ10, along with natural Vitamin E and beta-carotene helps balance free radicals and reduce damage from smoking, alcohol intake, exposure to toxins and radiation.*


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LEARN ABOUT COQ10


Chemical Name and Class

Ubiquinone (2,3-dimethoxy-5-methyl-6-decaprenyl-1,4-benzoquinone); quinone


Common Names

CoQ10, coenzyme Q10, coenzyme Q, ubidecarenone


General Description


CoQ10 is a naturally occurring lipid-soluble antioxidant and electron-transporting coenzyme available as a dietary supplement in the form of a yellow to orange crystalline powder. CoQ10 is a component of the respiratory chain and acts as an effective scavenger of oxygen free radicals known to inhibit the oxidation of LDL-cholesterol. It functions as a bioenergetic, being the coenzyme for mitochondrial enzyme complexes that ultimately produce cellular ATP. CoQ10 bears a close relationship with vitamin E which it allows to regenerate in its active, reduced form (α-tocopherol). It also serves in the regeneration of the reduced form of ascorbate.


Biochemcial Functions


Coenzyme Q10 is well defined as a crucial component of the oxidative phosphorylation process in mitochondria which converts the energy in carbohydrates and fatty acids into ATP to drive cellular machinery and synthesis. New roles for coenzyme Q10 in other cellular functions are only becoming recognized.

New aspects have developed from the recognition that coenzyme Q can undergo oxidation/reduction reactions in other cell membranes such as lysosomes, Golgi or plasma membranes. In mitochondria and lysosomes, coenzyme Q10 undergoes reduction/oxidation cycles during which it transfers protons across the membrane to form a proton gradient. The presence of high concentrations of quinol in all membranes provides a basis for antioxidant action either by direct reaction with radicals or by regeneration of tocopherol and ascorbate.

Evidence for a function in redox control of cell signaling and gene expression is developing from studies on coenzyme Q10 stimulation of cell growth, inhibition of apoptosis, control of thiol groups, formation of hydrogen peroxide and control of membrane channels. Deficiency of coenzyme Q10 has been described based on failure of biosynthesis caused by gene mutation, inhibition of biosynthesis by HMG coA reductase inhibitors (statins) or for unknown reasons in ageing and cancer. Correction of deficiency requires supplementation with higher levels of coenzyme Q10 than are available in the diet.



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