ESNATS - Embryonic Stem cell-based Novel Alternative Testing Strategies

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The EC-funded FP7 collaborative research project ESNATS (Embryonic Stem cell-based Novel Alternative Testing Strategies) aims at developing a novel toxicity test platform based on embryonic stem cells (ESCs), in particular human ESC (hESCs) to accelerate drug development, reduce related R&D costs and propose an alternative to animal tests. To reach these goals, ESNATS will develop a battery of toxicity tests using hESC lines subjected to standardised culture and differentiation protocols. Tests cover reproductive toxicity, neurotoxicity, metabolism and toxicokinetics and will be integrated into an

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