BiologyOfChronicDisease.org
Title
The Center for the Biology of Chronic Disease - Home
Description
that specializes in researching the biology of chronic disease. We believe that to device drugs that cure a chronic disease, such as cancer, heart disease, diabetes, or arthritis, we need to know the biology of that disease. The following section from Dr. Polansky's book on microcompetition (p. 31) can be used to explain what we mean by "the biology of a chronic disease":
"If, after disturbances, a system always returns to the same equilibrium, the equilibrium is called “stable.” Let “good health” be identified with a certain stable equilibrium. Any stable equilibrium different from “good health” will be called “chronic disease.” Exogenous events that produce new stable equilibria will be called “disruptions.” Specifically, the exogenous events that move a biological system from “good health” to “chronic disease” are disruptions. The disruptions responsible for most of the chronic diseases, such as, cancer , obesity , osteoarthritis , atherosclerosis , multiple sclerosis , type II and type I diabetes, and male pattern baldness , are mostly unknown. Moreover, even in cases where a disruption is identified, the molecular effects associated with the disruption, and the sequence of events leading from the disrupted molecular environment to clinical symptoms are unknown."
By "the biology of chronic disease" we mean the original disruption that causes the disease and the sequence of events that lead from the disruption to the clinical symptoms. We specialize in researching this biology. We hope that once the biology is clear, pharmaceutical and biotech companies will be able to formulate drugs that reverse the effects of the disruption, and therefore cure the disease, or even block the disruption, and therefore prevent the disease from developing in healthy individuals.
Languages
English
Contact
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- Rochester New York
- United States 14623
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- +1.5852925460
